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Brussels to Prague Bus

from £39.97

What to expect of your trip

Fast, easy, and affordable options from Brussels to Prague

Min. trip duration

13 hr 10 mins

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Min. distance

576 miles

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Cheapest trip

From £39.97

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29

Min. trips a day

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Digital ticket & live tracking

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On this page

Bus stations and stops in Brussels

Please note: your ticket will contain the most up-to-date address information.

Onboard services are subject to availability

Where to next?
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Vehicle passing through a city

Digital ticket & live tracking

Discover the FlixBus app

Book trips
Your tickets
Track your trip
Always in the know
Get it on Google Play Download on the App Store
FlixBus app on phone

Scan to download the App

Trusted by 500+ million passengers

Frequently asked questions

Coach tickets from Brussels to Prague start from £39.97. For the best fares, book early or choose midweek departures.
The route between Brussels and Prague generally takes about 13 hours 10 minutes by coach and covers approximately 579 miles.
On the coach from Brussels to Prague, you can bring one carry-on (30x42x18 cm, up to 7 kg) and one checked bag (50x80x30 cm, up to 20 kg) at no extra cost. Need more? You can add extra luggage or a bicycle when you book. For full details, check our luggage page.
The first coach service from Brussels to Prague is at 00:45.
The day's last coach departure from Brussels to Prague is set for 22:55.
No need to print your ticket. Just show the QR code from your confirmation email or the FlixBus app to the driver when you board your coach from Brussels to Prague.
FlixBus operates 4 coach stops in Brussels and 10 coach stops in Prague. Check the map above to find your pickup and drop-off points.
Yes, night coach services run from Brussels to Prague. Check the timetable and pick the option that works for you!
All coaches from Brussels to Prague are wheelchair accessible and equipped with boarding assistance. Service animals are welcome on board, and wheelchairs, walking aids, and other mobility devices travel free of charge. For full details, check our accessibility services page.
Coaches from Brussels to Prague come with free Wi-Fi, power outlets, extra legroom, and onboard toilets. You can also reserve a seat during booking, subject to availability. For the full list, check our onboard services page.

Coaches to Prague from Brussels: everything you need to know

  • Bus ticket price: you can travel between Brussels and Prague starting from £39.97.
  • Average duration: the bus from Brussels to Prague lasts approximately 13 hours 10 minutes.
  • Distance covered: the distance between Brussels and Prague is 579 miles, with some variation depending on the bus route and intermediate stops.
  • Brussels to Prague bus schedules: to check coach departure times between Brussels and Prague, select your travel data to view all available journeys, including timetables and prices. You’ll then be shown every available trip option with full schedules and fares. You can do this by using the selector at the top of the page or via the interactive map.
  • Bus departure frequency: about 29 departures per day.
  • Bus departure and drop off points: in Brussels, there are 4 coach stops. As for Prague, it has 10 stops.. You can locate the FlixBus stops on the map above on this page.
  • Night buses: night bus services are available to depart from Brussels in the evening and arrive at Prague in total comfort.
  • Weekend trips: with FlixBus, you can depart Brussels on Friday and return on Sunday for a perfect weekend getaway in Prague.