Rome to Prague Bus
from £78.99Connecting you to the world
Endless possibilities. Discover over 8,000 destinations across more than 40 countries.
Comfort on the go
Kick back with free Wi-Fi, power outlets, and extra leg space. That's what modern coaches are all about.
Choose, book, travel
From your screen to your seat in seconds. You do the booking, we'll take care of the rest.
Go together
Why put another car on the road when you can choose collective travel instead?
What to expect of your trip
Fast, easy, and affordable options from Rome to Prague
Min. trip duration
19 hr 55 mins
Min. distance
388 miles
Cheapest trip
From £78.99
35
Min. trips a day
On this page
Bus stations and stops in Rome
Rome Tiburtina bus station
Rome Anagnina
Rome Termini
Via Marsala 25
fronte Hotel Royal Santina
00185 Rome
Italy
fronte Hotel Royal Santina
00185 Rome
Italy
View this address on Google Maps
The stop is located in front of the Royal Santina Hotel (on the other side of the street)
Rome Vaticano
Rome Vaticano
Roma Aurelia
Rome Piazza Indipendenza
Roma Termini - Via Marsala
Best service on board
Available options you can find for a more comfortable trip:
Free WiFi
Stay connected throughout your journey
Power Outlets
Keep your devices charged on the go
Comfortable seats
Relax with extra legroom and reclining seats
Luggage storage
Space to safely stow your belongings
Toilets
Conveniently available on every FlixBus
First time travelling with us?
More on our service
Onboard services are subject to availability
Frequently asked questions
How much luggage can I bring on the coach from Rome to Prague?
How much is a bus ticket from Rome to Prague?
How long does it take to get to Prague from Rome by coach?
When's the first coach leaving Rome for Prague?
When's the last coach from Rome to Prague?
Do I need a printed ticket for my bus journey from Rome to Prague?
How many coach stops are in Rome and in Prague?
Are coaches from Rome to Prague equipped for passengers with mobility restrictions?
What onboard services are available on coaches from Rome to Prague?
Coaches to Prague from Rome: everything you need to know
- Bus ticket price: you can travel between Rome and Prague starting from £74.99.
- Average duration: the bus from Rome to Prague lasts approximately 19 hours 55 minutes.
- Distance covered: the distance between Rome and Prague is 841 miles, with some variation depending on the bus route and intermediate stops.
- Rome to Prague bus schedules: to check coach departure times between Rome and Prague, select your travel data to view all available journeys, including timetables and prices. You’ll then be shown every available trip option with full schedules and fares. You can do this by using the selector at the top of the page or via the interactive map.
- Bus departure frequency: about 34 departures per day.
- Bus departure and drop off points: in Rome, there are 7 coach stops. As for Prague, it has 11 stops.. You can locate the FlixBus stops on the map above on this page.
- Weekend trips: with FlixBus, you can depart Rome on Friday and return on Sunday for a perfect weekend getaway in Prague.
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