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Coach trips from St. Louis, MO to Chicago, IL

from £36.99

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What to expect of your trip

Fast, easy, and affordable options from St Louis, MO to Chicago, IL

Avg. trip duration

6 hr 33 mins

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Avg. distance

318 miles

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Cheapest trip

From £36.99

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2

Avg. trips a day

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On this page

Bus stations and stops in St Louis, MO

Please note: your ticket will contain the most up-to-date address information.
Best service on board
Available options you can find for a more comfortable trip:
wifi
Free WiFi
Stay connected throughout your journey
socket
Power Outlets
Keep your devices charged on the go
seat
Comfortable seats
Relax with extra legroom and reclining seats
luggage
Luggage storage
Space to safely stow your belongings
toilet
Toilets
Conveniently available on every FlixBus
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Frequently asked questions

Yes, all FlixBus coaches on the St Louis to Chicago route feature onboard restrooms.
Bus tickets from St Louis to Chicago with FlixBus are available from as low as £36.99.
The route between St Louis and Chicago generally takes about 6 hours 5 minutes by coach and covers approximately 319 miles.
Passengers travelling from St Louis to Chicago by coach are permitted to bring one piece of checked luggage (50x80x30 cm, up to 20 kg) and one hand luggage (30x42x18 cm, up to 7 kg) at no cost. For additional or special luggage, refer to this page. You can bring your bike with FlixBus, subject to availability. Check here for bike prices.
The first coach service from St Louis to Chicago is at 02:00.
The day's last coach departure from St Louis to Chicago is set for 23:30.
There's no requirement for a printed bus ticket for your journey between St Louis and Chicago. After completing your online booking, you'll receive an email containing a PDF with a QR code, which serves as your digital ticket. If you booked via the FlixBus App, your ticket will be saved there. Just present this digital QR code to the driver upon boarding.
In St Louis, there are 2 coach stops. As for Chicago, it has 3 stops.. You can locate the FlixBus stops on the map above on this page.
Yes, weekend bus options are available from St Louis to Chicago. You can depart on Friday and return on Sunday. Check the bus route’s schedule and choose the best trip to suit your plans!
Yes, night coach services run from St Louis to Chicago. Check the timetable and pick the option that works for you!
Every FlixBus coach between St Louis and Chicago is designed to cater to passengers with mobility constraints. We accommodate wheelchairs, folding chairs, and other mobility aids at no extra charge, and all trips welcome service animals to ensure accessible, comfortable travel.
Yes, most of our coaches on the St Louis -Chicago route are equipped with free WiFi.

Bus travel from St Louis to Chicago: everything you need to know

  • Bus ticket price: you can travel between St Louis and Chicago starting from £36.99 (average ticket cost: £40.99).
  • Average duration: the bus journey from St Louis to Chicago lasts approximately 6 hours 5 minutes.
  • Distance covered: the distance between St Louis and Chicago is 319 miles, with some variation depending on the bus route and intermediate stops.
  • Bus schedules St Louis-Chicago: to check departure times of coaches between St Louis and Chicago, select your travel date: you’ll then see all available trip options with their schedules and prices. You can do this using the selector at the top of this page or by using our interactive map.
  • Bus departure frequency: about 3 departures per day.
  • Bus departure and drop off points: in St Louis, there are 2 coach stops. As for Chicago, it has 3 stops.. You can locate the FlixBus stops on the map above on this page.
  • Night buses: night bus services are available to depart St Louis in the evening and arrive at Chicago in total comfort.
  • Weekend trips: with FlixBus, you can depart St Louis on Friday and return on Sunday for a perfect weekend getaway in Chicago.
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Onboard services are subject to availability