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Karlsruhe to Brno Bus

What to expect of your trip

Fast, easy, and affordable options from Karlsruhe to Brno

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Bus stations and stops in Karlsruhe

Please note: your ticket will contain the most up-to-date address information.

Onboard services are subject to availability

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Vehicle passing through a city

Digital ticket & live tracking

Discover the FlixBus app

Book trips
Your tickets
Track your trip
Always in the know
Get it on Google Play Download on the App Store
FlixBus app on phone

Scan to download the App

Trusted by 500+ million passengers

Frequently asked questions

The route between Karlsruhe and Brno generally takes about 12 hours 30 minutes by coach and covers approximately 502 miles.
On the coach from Karlsruhe to Brno, you can bring one carry-on (30x42x18 cm, up to 7 kg) and one checked bag (50x80x30 cm, up to 20 kg) at no extra cost. Need more? You can add extra luggage or a bicycle when you book. For full details, check our luggage page.
The first coach service from Karlsruhe to Brno is at 02:15.
The day's last coach departure from Karlsruhe to Brno is set for 23:25.
No need to print your ticket. Just show the QR code from your confirmation email or the FlixBus app to the driver when you board your coach from Karlsruhe to Brno.
FlixBus operates 54 coach stops in Karlsruhe and 4 coach stops in Brno. Check the map above to find your pickup and drop-off points.
Yes, night coach services run from Karlsruhe to Brno. Check the timetable and pick the option that works for you!
All coaches from Karlsruhe to Brno are wheelchair accessible and equipped with boarding assistance. Service animals are welcome on board, and wheelchairs, walking aids, and other mobility devices travel free of charge. For full details, check our accessibility services page.
Coaches from Karlsruhe to Brno come with free Wi-Fi, power outlets, extra legroom, and onboard toilets. You can also reserve a seat during booking, subject to availability. For the full list, check our onboard services page.