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Coach trips from Indianapolis, IN to St. Louis, MO

from £27.99

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What to expect of your trip

Fast, easy, and affordable options from Indianapolis, IN to St Louis, MO

Avg. trip duration

3hr23mins

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Avg. distance

244 miles

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Cheapest trip

From £27.99

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3

Avg. trips a day

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On this page

Bus stations and stops in Indianapolis, IN

Please note: your ticket will contain the most up-to-date address information.
Best service on board
Available options you can find for a more comfortable trip:
wifi
Free WiFi
Stay connected throughout your journey
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Power Outlets
Keep your devices charged on the go
seat
Comfortable seats
Relax with extra legroom and reclining seats
luggage
Luggage storage
Space to safely stow your belongings
toilet
Toilets
Conveniently available on every FlixBus
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Frequently asked questions

Yes, all FlixBus coaches on the Indianapolis to St Louis route feature onboard restrooms.
Bus tickets from Indianapolis to St Louis with FlixBus are available from as low as £27.99.
The route between Indianapolis and St Louis generally takes about 2 hours 55 minutes by coach and covers approximately 243 miles.
Passengers travelling from Indianapolis to St Louis by coach are permitted to bring one piece of checked luggage (50x80x30 cm, up to 20 kg) and one hand luggage (30x42x18 cm, up to 7 kg) at no cost. For additional or special luggage, refer to this page. You can bring your bike with FlixBus, subject to availability. Check here for bike prices.
The first coach service from Indianapolis to St Louis is at 03:30.
The day's last coach departure from Indianapolis to St Louis is set for 20:05.
There's no requirement for a printed bus ticket for your journey between Indianapolis and St Louis. After completing your online booking, you'll receive an email containing a PDF with a QR code, which serves as your digital ticket. If you booked via the FlixBus App, your ticket will be saved there. Just present this digital QR code to the driver upon boarding.
In Indianapolis, there are 4 coach stops. As for St Louis, it has 2 stops.. You can locate the FlixBus stops on the map above on this page.
Yes, weekend bus options are available from Indianapolis to St Louis. You can depart on Friday and return on Sunday. Check the bus route’s schedule and choose the best trip to suit your plans!
Every FlixBus coach between Indianapolis and St Louis is designed to cater to passengers with mobility constraints. We accommodate wheelchairs, folding chairs, and other mobility aids at no extra charge, and all trips welcome service animals to ensure accessible, comfortable travel.
Yes, most of our coaches on the Indianapolis -St Louis route are equipped with free WiFi.

Bus travel from Indianapolis to St Louis: everything you need to know

  • Bus ticket price: you can travel between Indianapolis and St Louis starting from £27.99.
  • Average duration: the bus journey from Indianapolis to St Louis lasts approximately 2 hours 55 minutes.
  • Distance covered: the distance between Indianapolis and St Louis is 243 miles, with some variation depending on the bus route and intermediate stops.
  • Bus schedules Indianapolis-St Louis: to check departure times of coaches between Indianapolis and St Louis, select your travel date: you’ll then see all available trip options with their schedules and prices. You can do this using the selector at the top of this page or by using our interactive map.
  • Bus departure frequency: about 3 departures per day.
  • Bus departure and drop off points: in Indianapolis, there are 4 coach stops. As for St Louis, it has 2 stops.. You can locate the FlixBus stops on the map above on this page.
  • Weekend trips: with FlixBus, you can depart Indianapolis on Friday and return on Sunday for a perfect weekend getaway in St Louis.
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Onboard services are subject to availability