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St Louis, MO to Indianapolis, IN Bus

from £26.49

What to expect of your trip

Fast, easy, and affordable options from St Louis, MO to Indianapolis, IN

Avg. trip duration

5 hr 32 mins

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Avg. distance

244 miles

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Cheapest trip

From £26.49

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3

Avg. trips a day

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On this page

Bus stations and stops in St Louis, MO

Please note: your ticket will contain the most up-to-date address information.

Onboard services are subject to availability

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Frequently asked questions

Passengers travelling from St Louis to Indianapolis by coach are permitted to bring one piece of checked luggage (50x80x30 cm, up to 20 kg) and one hand luggage (30x42x18 cm, up to 7 kg) at no cost. For additional or special luggage, refer to this page. You can bring your bike with FlixBus, subject to availability. Check here for bike prices.
Yes, all FlixBus coaches on the St Louis to Indianapolis route feature onboard restrooms.
Yes, most of our coaches on the St Louis -Indianapolis route are equipped with free WiFi.
Every FlixBus coach between St Louis and Indianapolis is designed to cater to passengers with mobility constraints. We accommodate wheelchairs, folding chairs, and other mobility aids at no extra charge, and all trips welcome service animals to ensure accessible, comfortable travel.
Yes, weekend bus options are available from St Louis to Indianapolis. You can depart on Friday and return on Sunday. Check the bus route’s schedule and choose the best trip to suit your plans!
In St Louis, there are 2 coach stops. As for Indianapolis, it has 4 stops.. You can locate the FlixBus stops on the map above on this page.
There's no requirement for a printed bus ticket for your journey between St Louis and Indianapolis. After completing your online booking, you'll receive an email containing a PDF with a QR code, which serves as your digital ticket. If you booked via the FlixBus App, your ticket will be saved there. Just present this digital QR code to the driver upon boarding.
The day's last coach departure from St Louis to Indianapolis is set for 13:55.
The first coach service from St Louis to Indianapolis is at 02:00.
The route between St Louis and Indianapolis generally takes about 5 hours 25 minutes by coach and covers approximately 244 miles.
Bus tickets from St Louis to Indianapolis with FlixBus are available from as low as £26.49.

Bus travel from St Louis to Indianapolis: everything you need to know

  • Bus ticket price: you can travel between St Louis and Indianapolis starting from £26.49.
  • Average duration: the bus journey from St Louis to Indianapolis lasts approximately 5 hours 25 minutes.
  • Distance covered: the distance between St Louis and Indianapolis is 244 miles, with some variation depending on the bus route and intermediate stops.
  • Bus schedules St Louis-Indianapolis: to check departure times of coaches between St Louis and Indianapolis, select your travel date: you’ll then see all available trip options with their schedules and prices. You can do this using the selector at the top of this page or by using our interactive map.
  • Bus departure frequency: about 3 departures per day.
  • Bus departure and drop off points: in St Louis, there are 2 coach stops. As for Indianapolis, it has 4 stops.. You can locate the FlixBus stops on the map above on this page.
  • Weekend trips: with FlixBus, you can depart St Louis on Friday and return on Sunday for a perfect weekend getaway in Indianapolis.